Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Oral manifestations of infections due to varicella zoster virus in otherwise healthy children
1Oral Medicine and Pathology, Dental School of Aristotle University of Thessaloniki, Greece
2Preventive Dentistry and Periodontology, Dental School of Aristotle University of Thessaloniki, Greece
3Private Dentist, Greece.
DOI: 10.17796/jcpd.25.2.p255673211764073 Vol.25,Issue 2,April 2001 pp.107-112
Published: 01 April 2001
Varicella zoster virus (VZV) causes varicella (or chickenpox) and establishes latency in nerve ganglia after the primary infection. The reactivation of virus later in life can cause mono- or polyneuropathy. The cranial nerves most commonly involved are five (herpes zoster or shingles), six, seven eight, nine and ten. In the present study we describe the oral lesions associated with VZV infections in normal children. In a 3 year period we examined 62 children, age 2 to 13 years old with diagnosed varicella and a 4 year old boy with herpes zoster at the 3rd branch of the trigeminal nerve.According to the clinical picture of varicella, the disease was defined as: (1) group A mild cases; (2) group B moderate cases; (3) group C severe. The manifestations of varicella were: mild varicella 19 children, moderate 26 children and severe 17 children. The results of the present study indicate that the prevalence of oral manifestations of varicella is related to the severity of the disease. In 17 severe cases, oral lesions were always present and the number was between 5 to 30. From 26 moderate cases, oral lesions were observed in 23 and the number was between 2 to 10. From 19 mild cases, oral lesions were present only in 6 cases and their number was 1 or 2. Often varicella’s oral lesions resemble manifestations of other entities, and this may cause differential diagnostics problems.
Alexandros Kolokotronis,Konstantinos Louloudiadis,Garyfalia Fotiou,Apostolos Matiais. Oral manifestations of infections due to varicella zoster virus in otherwise healthy children. Journal of Clinical Pediatric Dentistry. 2001. 25(2);107-112.
1. Arvin AM Varicella-zoster virus: overview and clinical manifestations. SeminDermatol 15 (2 Suppl I): 4-7, 1996.
2. Dueland AN, Ranneberg-Nilsen T, Degre M. Detection of latent varicella zoster virus DNA and human gene sequence in trigeminal ganglia by in situ amplification combined with in situ hybridization. Arch Virol 140: 2005-2066, 1995.
3. Turner JE, Geunes PM, Schuman NJ. Cranial polyneuropathyRamsay Hunt’s syndrome. Case report and discussion. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83: 57-57, 1997.
4. Pevenstein SR. Williams RK, McChenecy D, Mont EK, Smialek JE, Straus SE. Quantitation of latent varicella-zoster virus and herpes simplex virus in human trigeminal ganglia. J Virol 73: 105 14-10518, 1999.
5. Ohashi T, Fujimoto M, Shimizu U, Atsumi T. A case of isolated vagus nerve pasly with herpes zoster. Rinso Shinkeigaku 34: 928- 929, 1994.
6. Cicala 5, DiCiommo V. Massini R. Cephalic zoster with involvement of the 5th 7th 8th, 9th and l0th right cranial nerves. Minerva Med 68: 4253-4256, 1977.
7. Chretien F, Belec L, Lescs MC, Autier FJ, De-Truchis P, Scaravilli F, Grey F. Central nervous system infection due to varicella and zoster virus in AIDS. Arch Anat Cytol Pathol 45: 142-152, 1997.
8. Pedersen A, Hornsleth A. Recurrent aphthous ulceration: a possible clinical manifestation of reactivation of varicella zoster or cytomegalovirus infection. J Oral Pathol Med 22: 64-68, 1993.
9. Pedersen A, Madsen HO, Vestergaad BF, Ryder LP. Varicellazoster virus DNA in recurrent aphthous ulcers. Scand J Dent Res 101: 311-313, 1993.
10. Ghodratnama F, Riggio MP, Wray D. Search for human herpesvirus-6, human cytomegalovirus and varicella zoster virus DNA in recurrent aphthous stomatitis. J Oral Pathol Med 26: 192-197, 1997.
11. Brice SL, Cook D, Leahy M, Huff JC, Weston WL. Examination of the oral mucosa and peripheral blood cells of patients with reccurent aphthous ulceration for human herpesvirus DNA. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89: 193-198, 2000.
12. Fenton SJ, Unkel JH. Viral infections of the oral mucosa in children: A clinical review. Pract Period Aesth Dent 9: 683-692, 1997.
13. Piette ML. Herpes zoster at school-age: A case presentation and discussion of the unique aspects within the pediatric population. Haw Med J 55: 118-121, 1996.
14. Kakourou T, Theodoridou M, Mostrou G, Syriopoulou V, Papadogeorgaki H, Constantopoulos A. Herpes zoster in children. J Am Acad Dermatol 31: 207-12, 1998.
15. Whallett U, Pahor AL. Herpes and the head and neck: the difficulties in diagnosis. J Laryngol Otol 113: 573-577, 1999.
16. Schubert MIM. Oral manifestation of viral infections in immunocompromised patients. Curr Opin Dent 1: 384-397, 1991.
17. Straus SE. The management of varicella and zoster infections. Infect Dis North Am 1: 367-83, 1987.
18. Carcao MD, Lau RC, Gupta A, Huerter H, Keren G, King SM. Sequential use of intravenous and oral acyclovir in the therapy of varicella in immunocompromised children. Pediatr infect Dis J 17: 626-63, 1998.
19. Lynfield R, Herrin JT, Rubbin RH. Varicella in pediatric renal transplant recipients. Pediatrics 90: 216-220, 1992.
20. Meszner Z, Nyerges G, Bell AR, Oral acyclovir to prevent dissemination of varicella in immunocompromised children. J Infect 26: 9-15, 1993.
21. Kavaliotis G, Loukou I, Trachana M, Tsagaropoulou-Stigga H, Koliouskas D. Outbreak of varicella in a pediatric oncology unit. Med Pediatr Oncol 31: 166-169, 1998.
22. Brisson M, Edmunds WJ, Gay NJ, Law B, De Serres G. Analysis of varicella vaccine breakthrough rates: implications for the effectiveness of immunisation programmes. Vaccine 18: 2775- 2778, 2000.
23. Plotkin SA, Staar SE, Connor K, Morton D. Zoster in normal children after varicella vaccine. J Infect Dis 159: 1000-1001, 1989.
24. Matsubara K, Nigami H, Harigaya H, Baba K. Herpes zoster in a normal child after vaccination. Patient report. Acta Paediatr Jap 37: 648-650, 1995.
25. Greenberg MS. Herpesvirus infections. Dent Clin North Am 40: 359-368, 1996.
26. Fury J, Gilain L, Peynegre R. Les manifestations buccales du zona. A propos dun cas. Ann Oto-Laryng 110: 170-172, 1992.
27. Sigurdsson A, Jacoway JR. Herpes zoster infection presenting as an acute pulpitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80: 92-95, 1995.
28. Schauf V, Tolpin M. Varicella-zoster virus. In: Belshe RB, ed Textbook of oral virology. Littleton Mass. RSG Pub Comp Inc, pp 829-850, 1984.
29. Terada K, Kawano 5, Yoshihiro K, Miyashima H, Morita T. Characteristics of herpes zoster in otherwise normal children. Ped Infect Dis 12: 960-961, 1993.
30. Paryani SG. Arvin AM. Intrauterine infection with VZV after maternal varicella. N Eng J Med 314: 542-546, 1986.
31. Rothe MJ, Feder HM, Grant-Kels JM. Oral acyclovir therapy for varicella and zoster infections in pediatric and pregnant patients: A brief review. Ped Derm 8: 236-242, 1991.
32. Arvin AM. Management of varicella zoster virus infections in children. Adv Exp Med Biol 458: 167-174, 1999.
Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.
Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.
Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.
JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.
Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.
BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.
Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.
Scopus: CiteScore 1.8 (2023) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.
Top