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Open AccessEvaluation of Levels of Nitric Oxide in Saliva of Children with Rampant Caries and Early Childhood Caries :A Comparative Study
Evaluation of Levels of Nitric Oxide in Saliva of Children with Rampant Caries and Early Childhood Caries :A Comparative Study
1Department of Pedodontics and Preventive Children Dentistry, A.B. Shetty Memorial Institute of Dental Sciences
2Department of Pedodontics and Preventive Children Dentistry, A.B. Shetty Memorial Institute of Dental Sciences
3Department of Biochemistry, K.S. Hegde Medical Academy
DOI: 10.17796/jcpd.32.4.4010kl5262687528 Vol.32,Issue 4,July 2008 pp.283-286
Published: 01 July 2008
*Corresponding Author(s): Amitha M. Hegde E-mail: amipedo@yahoo.co.in dr_neekhra@yahoo.com
Abstract
It is considered that caries incidence might be low in subjects with high salivary Nitric Oxide (NO) levels. Thus the objective of the present study was to determine the levels of nitric oxide in saliva of children with Rampant Caries (RC) and Early Childhood Caries (ECC). A total of 120 children were divided into 4 groups of 30 each belonging to two age groups of 6-12 yrs and 71 months or less respectively. Children between the age of 6-12 yrs were either with RC or their control and children between the age of 71months or less were either with ECC or their control respectively. The study and control subjects were divided equally. Oral health status was recorded followed by unstimulated salivary flow rate estimation. Estimation of salivary nitric oxide was measured by the concentration of its stable metabolite nitrite using Classical Griess Reaction. The mean nitrite levels of both the control groups were much higher when compared with the study groups, which was statistically very highly significant.
Keywords
Nitrate; Nitrite; Nitric Oxide; Rampant Caries; Early Childhood Caries; Salivary Flow Rate
Cite and Share
Amitha M. Hegde,Varun Neekhra,Suchetha Shetty. Evaluation of Levels of Nitric Oxide in Saliva of Children with Rampant Caries and Early Childhood Caries :A Comparative Study. Journal of Clinical Pediatric Dentistry. 2008. 32(4);283-286.
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