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Original Research

Open Access

Factor XIII Deficiency: Report of Two Cases

  • Poornima P1
  • Shashibhushan K K1
  • Bharath K P1,*,
  • Subba ReddyV V1

1Department of Pedodontics and Preventive Dentistry, College of Dental Sciences, Davangere, Karnataka, India.

DOI: 10.17796/jcpd.35.1.a377042248788418 Vol.35,Issue 1,January 2011 pp.101-104

Published: 01 January 2011

*Corresponding Author(s): Bharath K P E-mail: dr_bharatkp@yahoo.co.in bha.dentist@gmail.com

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Abstract

Factor XIII deficiency is one of the rare clotting factor deficiencies. Although rare, it is an important disorder because of seriousness of its bleeding manifestations, in particular the incidence of intracranial hemorrhage is higher than any other bleeding disorder. Hence an early diagnosis is extremely important where bleeding manifestations can be prevented by prophylactic factor XIII replacement given at every 4-6 week interval. Case1 presents the management of a factor deficiency associated with a very rare blood group AB+ve, while the case 2 reports the successful surgical management with a replacement therapy.

Keywords

Factor XIII deficiency, Clotting factor deficiency, children, dental management.

Cite and Share

Poornima P,Shashibhushan K K,Bharath K P,Subba ReddyV V. Factor XIII Deficiency: Report of Two Cases. Journal of Clinical Pediatric Dentistry. 2011. 35(1);101-104.

URL:

https://www.jocpd.com/articles/10.17796/jcpd.35.1.a377042248788418

References

1. Hsieh. L. Nugent.D. factor XIII deficiency. Hemophilia.14(6): 1190–1200, 2008

2. H. Suzuki, T. Kaneda. Tooth extraction in two patients who had a congenital deficiency of factor XIII. Journal of Oral and Maxillofacial Surgery, Vol. 43(3); 221–24, 1985.

3. Kitchens CS, Newcomb TF: Factor XIII. Medicine, 58: 413–29, 1979

4. Colin W, Needleman HL.Medical/dental Management of a Patient With Congenital Factor XIII Deficiency. Pediatric Dent, 7(3): 227–30, 1985

5. Eshghi P,. Mahjour S. B. Naderi M, Dehbozorgian. J. and. Karimi. M. Long term prophylaxis in patients with factor XIII deficiency complicated by intracranial haemorrhage in Iran. Hemophilia, 15: 1–2, 2009

6. Anwar R, Miloszewki KJA, Factor XIII deficeiency Br J Haematology, 107: 468–84, 1999

7. Eshghi P, Abdolghasemi H, Sanei Moghaddam E Anwar R Jazebi M Ala. R. Factor XIII deficiency in south eastren iran. Hemophilia, 10: 470–2, 2004.

8. Israels ED, Paraskevas F, Israels LG: Immunological studies of coagulation factor FXIII. J Clin Invest, 52: 2398–2403, 1973

9. Redeghiero F: Subunit A and S inheritance in four families with congenital factor XIII deficiency. Br J Haemat, 38: 267–71, 1978.

10. Francis J, Todd P, Congenital factor XIII deficiency in a neonate. Br Med J, 12: 1552, 1978

11. W Onland, A N Böing, A B Meijer, M C L Schaap, R Nieuwland, K Haasnoot, A Sturk, M Peters. Congenital deficiency of factor XIII caused by two missense mutations in a Dutch family. Hemophilia,11: 539–547, 2005.

12. Ronald Hoffman, Edward J. Benz, Jr, Sanford J. Shattil, Bruce Furie, Harvey J. Cohen, and Leslie E. Silberstein (eds). Priniciples and practice.Hematology. 2nd edition. New York, NY, Churchill Livingstone, 1995.

13. Zech R, Strother SV; Maintainance of hemostasis during exodontia in two hemophilics with factor VIII inhibition. J oral. Maxillofac Surg, 41; 53–56, 1983

14. Miloszewski K Losowsky MS The half life of factor XIII in vivo. Br J Hemotol, 19: 685–90, 1970. 15. Francis JL. The detection and measurement of factor XIII activity: A review. Med Lab Sci, 37: 137, 1980.

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