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Original Research

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Efficacy of Mineral Trioxide Aggregate as an Apical Plug in Non-Vital Young Permanent Teeth: Preliminary Results

  • Sankar Annamalai1
  • Jayanthi Mungara1,*,

1Department Of Pedodontics and Preventive Dentsitry, Ragas Dental College and Hospital, 2/102, East Coast Road, Uthandi, Chennai – 600 119, Tamil Nadu, India.

DOI: 10.17796/jcpd.35.2.9061h7g718834017 Vol.35,Issue 2,March 2011 pp.149-156

Published: 01 March 2011

*Corresponding Author(s): Jayanthi Mungara E-mail: dras4me@yahoo.co.in jayanthi_1963@yahoo.co.in

Abstract

The purpose of this study was to evaluate the efficacy of Mineral trioxide aggregate (MTA) clinically and radiographically as material used to induce root end closure in nonvital permanent teeth with immature apices (apexification) in children. Methods: The study included 30 non vital young permanent, single rooted teeth of 22 children between 8 and 13 years of age. Treatment followed a standard non-surgical root canal treatment protocol and the root canal was filled with a apical plug of 4-5 mm of MTA (white MTA – Angelus, Brazil), followed by gutta-percha obturation. The children were reviewed for 1 year at 3 month interval and the teeth were assessed clinically and radiographically. Results: MTA showed success rate of 100% both clinically and radiographically at the 12th months follow up and root end closure was seen in 86.6% of cases and root growth in 30% of cases. Conclusions: MTA showed clinical and radiographic success as an apexification material by inducing root end closure and root growth in non-vital young permanent teeth.

Keywords

Apexification, Mineral trioxide aggregate (MTA), non-vital young permanent teeth, apical plug, open apex.

Cite and Share

Sankar Annamalai,Jayanthi Mungara. Efficacy of Mineral Trioxide Aggregate as an Apical Plug in Non-Vital Young Permanent Teeth: Preliminary Results. Journal of Clinical Pediatric Dentistry. 2011. 35(2);149-156.

References

1. Walton RE, Torabinejad M. Management of incompletely formed roots. In: Principles and Practice of Endodontics. 3rd ed. Philadelphia, Pa: WB Saunders; 388–404, 2002.

2. Lieberman J & Trowbridge H. Apical closure of nonvital permanent incisor teeth where no treatment was performed: Case Report. J Endod, 9(3): 257–260, 1983.

3. Das S. Apexification in a nonvital tooth by control of infection. J Am Dent Assoc, 100: 880–881, 1980.

4. Ham JW, Patterson SS, Mitchell DF. Induced apical closure of immature pulpless teeth in monkeys. J Oral Surg, 33: 438–448, 1972.

5. Ball JS. Apical root formation in a nonvital immature permanent incisor. Br Dent J, 116: 116–117, 1964.

6. Frank A. Therapy for divergent pulpless tooth by continued apical formation. J Am Dent Assoc, 72: 87–93, 1966.

7. Coviello J & Brilliant JD. A preliminary clinical study on the use of tricalcium phosphate as an apical barrier. J Endod, 5(1): 6–13, 1979.

8. Hayashi Y & Imai M. Application of Ca-β-Glycerophosphate for artificial apical barrier formation. J Endod, 21(4): 205–7, 1995.

9. Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endodon, 25(3): 197–205, 1999.

10. Dimashkieh MR. The problem of open apex – a new approach: Oxidised regenerated cellulose technique. J Br Enodod Soc, 10(1): 9–16, 1977.

11. Brandell DW, Torabinejad M, Bakland LK, Lessard GM. Demineralized dentin, hydroxyapatite and dentin chips as apical plugs. Endod Dent Traumatol, 2: 210–4, 1986.

12. Shabahang S, Torabinejad M, Boyne PP, Abedi H, and McMillan P. A comparative study of root-end induction using Osteogenic protein-I, Calcium hydroxide, and Mineral Trioxide Aggregate in dogs. J Endod, 25(1): 1–5, 1999.

13. Yoshida T, Itoh T, Saitoh T, Sekine I. Histopathological study of the use of freeze-dried allogenic dentin powder and true bone ceramic as apical barrier materials. J Endodon, 24: 581–6, 1998.

14. Binnie WH, Mitchell DF. Induced calcification in the subdermal tissues of the rat. J Dent Res, 52: 1087, 1973.

15. Finucane D, Kinirons MJ. Non-vital immature permanent incisors: factors that may influence treatment outcome. Endod Dent Traumatol, 15: 273–7, 1999.

16. Yates JA. Barrier formation time in non-vital teeth with open apices. Int Endod J, 21: 313–9, 1988.

17. Andreasen JO, Farik B, Munksgaard EC. Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dent Traumatol, 18: 134–7, 2002.

18. Andersen M. Invitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite. Endod Dent Traumatol, 8: 104, 1992.

19. Torabinejad M, Hong CU, McDonald F, Pitt-Ford T. Physical and chemical properties of a new root-end filling material. J Endodon, 21(7): 349–53, 1995.

20. Koh ET, McDonald F, Pitt Ford TR, Torabinejad M. Cellular response to mineral trioxide aggregate. J Endodon, 24: 543–7, 1998.

21. Torabinejad M, Hong CU, Pitt Ford and Kettering JD. Cytotoxicity of four root end filling materials. J Endodon, 21(10): 489–92, 1995.

22. Torabinejad M, Hong CU, Pitt Ford TR, and Kariyawasam SP. Tissue reaction to Implanted Super-EBA and Mineral Trioxide Aggregate in the Mandible of Guinea Pigs: A Preliminary Report. J Endo, 21(11): 569–71, 1995.

23. Shabahang S, Torabinejad M. Treatment of teeth with open apices using mineral trioxide aggregate. Pract Periodontics Aesthet Dent, 12: 315–20, 2000.

24. Steinig TH, Regan JD, Gutmann JL. The use and predictable placement of mineral trioxide aggregate in one-visit apexification cases. Aust Endod J, 29: 34–42, 2003.

25. Witherspoon DE, Ham K. One-visit apexification: technique for inducing root-end barrier formation in apical closures. Pract Proced Aesthet Dent, 13: 455–60, 2001.

26. Vidya Saraswathi M, Kundabala M., Shashirashmi A. Conventional Vs rapid treatment modalities for wide canals. J Indian Soc. Endodon, 17(1): 5–17, 2005.

27. Moorrees CFA, F’anning EA, Hunt EE. Age variation of formation stages for ten permanent teeth. J Dent Res, 4: 1490–502, 1963.

28. Sarris S, Tahmassebi JF, Duggal MS, Cross IA. A clinical evaluation of mineral trioxide aggregate for root-end closure of non-vital immature permanent incisors in children: a pilot study. Dental Trauma, 24: 79–85, 2008.

29. Martin RL, Monticelli F, Brackett WW, Loushine RJ, Rockman RA, Ferrari M, Pashley DH & Tay FR. Sealing properties of Mineral Trioxide Aggregate orthograde apical plugs and root fillings in an in vitro apexification model. J Endod, 33: 272–275, 2007.

30. Gancedo-Caravia L & Garcia-Barbero E. Influence of humidity and setting time on the push-out strength of mineral trioxide aggregate obturations. J Endod, 32(9): 894–896, 2006.

31. Walker MP, Adam Diliberto & Charles Lee. Effect of Setting Conditions on Mineral Trioxide Aggregate Flexural Strength. J Endod, 32(4): 334–336, 2006.

32. El Meligy OAS & Avery DR. Comparison of apexification with Mineral Trioxide Aggregate and Calcium hydroxide. Pediatr Dent, 28: 248–253, 2006.

33. Pradhan DP, Chawla HS, Gauba K and Goyal A. Comparative evaluation of endodontic management of teeth with unformed apices with MTA and calcium hydroxide. J Dent Child, 73: 2, 79–85, 2006.

34. European Society of Endodontology. Consensus report of the European Society of Endodontology on quality guidelines for endodontic treatment. Int Endod J, 27: 115–24, 1994.

35. AAPD Guidelines. Guideline on Pulp Therapy for Primary and Immature Permanent Teeth. Pediatr. Dent. Referrence Manual, 30(7): 170–4, 2008–09.

36. Bortoluzzi EA, Araujo GS, Tanomaru JMG, and Tanomaru-Filho M. Marginal gingiva discoloration by gray MTA: A Case Report. J Endod, 33: 325–327, 2007.

37. Wein Fs. Alternatives to routine endodontic treatment. In: Weine FS, editor. Endodontic therapy. St. Louis: Mosby; 513–45, 2004.

38. Felippe WT, Felippe MCS & Rocha MJC. The effect of mineral trioxide aggregate on the apexification and periapical healing of teeth with incomplete root formation. Int Endod J, 39: 2–9, 2006.

39. Ghaziani P, Rastegar AF, Bidar M, Sadeghi G & Chegin P. Clinical and radiographic evaluations of success rate with MTA plug in open apices. Iran Endod J, 1(1): 15–18, Spring 2006.

40. Simon S, Rilliard F, Berdal A & Machtou P. The use of mineral trioxide aggregate in one-visit apexification treatment: a prospective study. Int Endo J, 40: 186–197, 2007.

41. Holden DT, Schwartz SA, Kirkpatrick TC & Schindler WG. Clinical outcomes of artificial root-end barriers with Mineral Trioxide Aggregate in teeth with immature apices. J Endod, 34(7): 812–817, 2008.

42. Torabinejad M, Hong CU, Pitt Ford and Kettering JD. Antibacterial Effects of Some Root End Filling Materials. J Endod, 21(8): 403–7, 1995.

43. Pitt Ford TR, Torabinejad M, McKendry DJ, Hong Cu & Kariyawasam SP. Use of Mineral trioxide aggregate for repair of furcal perforations. Oral Surg Oral Med Oral Pathol, 79: 756–762, 1995.

44. Torabinejad M, Hong CU, Lee SJ, Monsef M, and Pitt Ford TR. Investigation of Mineral Trioxide Aggregate for root-end filling in dogs. J Endod, 21(12): 603–8, 1995.

45. Erdem AP & Elif Sepet. Mineral trioxide aggregate for obturation of maxillary central incisors with necrotic pulp and open apices. Dent Traumatol, 24(5): 38–41, 2008.

46. Torabinejad M, Pitt Ford TR, McKendry DJ, Abedi HR, Miller DA and Kariyawasam SP. Histologic Assessment of Mineral Trioxide Aggregate as a Root-End Filling in Monkeys. J Endod, 23(4): 225–9, 1997.

47. Hunter AR, Kirk EE, Robinson DH, Kardos TB. A slow release calcium delivery system for the study of reparative dentine formation. Endod Dent Traumatol, 14: 112–8, 1998.

48. Takita T, Hayashi M, Takeichi O, Ogiso B, Suzuki N, Otsuka K & Ito K. Effect of mineral trioxide aggregate on proliferation of cultured human dental pulp cells. Int Endod J, 39: 415–422, 2006

49. Schroder U. Effects of calcium hydroxide-containing pulp-capping agents on pulp cell migration, proliferation, and differentiation. J Dent Res, 64: 541–8, 1985.

50. Torneck CD, Moe H, Howley TP. The effect of calcium hydroxide on porcine pulp fibroblasts in vitro. J Endod, 9: 131–6, 1983.

51.Holland R. Histochemical response of amputed pulps to calcium hydroxide. Rev Bras Pesq Med Biol, 4: 83–95, 1971.

52. Holland R, Souza V, Nery MJ, Faraco Júnior IM, Bernabe PFE, Otoboni Filho JA, Dezan Junior E. Reaction of rat connective tissue to implanted dentin tube filled with mineral trioxide aggregate, Portland cement or calcium hydroxide. Braz Dent J, 12(1): 3–8, 2001.

53. Holland R, Mazuqueli L, de Souza V, Murata SS, Dezan Júnior E, Suzuki P. Influence of the type of vehicle and limit of obturation on apical and periapical tissue response in dogs’ teeth after root canal filling with Mineral Trioxide Aggregate. J Endod, 33: 693–697, 2007.

54. Seux D, Couble ML, Hartmann DJ, Gauthier JP, Magloise H. Odontoblast-like cytodifferentiation of human dental pulp cells in vitro in the presence of calcium hydroxide containing cement. Arch Oral Biol, 36: 117–28, 1991.

55. Foreman PC, Barnes IE. A review of calcium hydroxide. Int Endod J, 23: 283–297, 1990.

56. Bonson S, Jeansonne BG & Lallier TE. Root-end filling materials alter fibroblast differentiation. J Dent Res, 83(5): 408–413, 2004.

57. Guven G, Cehreli ZC, Ural A, Serdar MA & Basak F. Effect of Mineral Trioxide Aggregate cements on Transforming Growth Factor β1 and Bone Morphogenetic Protein production by Human Fibroblasts in vitro. J Endod, 33: 447– 450, 2007.

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