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Original Research

Open Access

Toxic Epidermal Necrolysis. A case report

  • Patricia Villalta1
  • Ines Velez1,*,
  • Lina Mejia1
  • Ana Maria Ospina1

1MS Pediatric dentistry, Nova Southeastern University, College of Dental Medicine, Florida, USA.

DOI: 10.17796/jcpd.35.2.w824062838u53t22 Vol.35,Issue 2,December 2010 pp.197-198

Published: 01 December 2010

*Corresponding Author(s): Ines Velez E-mail: ivelez@nova.edu

Abstract

We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the epithelium. Severe sequelae, including blindness, hearing loss, tooth malformation and esophageal destruction are seen in this case.

Keywords

Toxic Epidermal Necrolysis, Steven Johnson Syndrome.

Cite and Share

Patricia Villalta,Ines Velez,Lina Mejia,Ana Maria Ospina. Toxic Epidermal Necrolysis. A case report. Journal of Clinical Pediatric Dentistry. 2010. 35(2);197-198.

References

1. Letko E, Papaliodis DN, Papaliodis GN,et al. Steven Johnson syndrome and toxic epidermal necrolysis: a review of the literature. Ann Allergy Asthma Immunol, 94: 419–21, 2005.

2. Bastuji-Garin S, Rzany B, Stern RS, et al. Clinical classification of cases of toxic epidermal necrolyisis, Steven Johnson syndrome and erythema multiforme. Arch Dermatol, 129: 192–95, 1993.

3. Roujeau JC, Stevens Johnson syndrome and toxic epidermal necrolysis are severity variants of the same disease which differs from erythema multiforme. J Dermatol, 24: 726–29, 1997.

4. Mockenhaupt M, Kelly JP, Kaufman D, Stern RS. The risk of Stevens Johnson syndrome and toxic epidermal necrolysis associated with nonsteroidal anti-inflammatory drugs: a multinational perspective. J Rheumatol, 30: 2234–40, 2003.

5. Gorlin RJ, Cohen MM,Hennekam RCN. Syndromes affecting skin and mucosa in syndromes of the head and neck. 4 Ed. McGraw Hill, 2001: 540–550.

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