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Dental Adhesion: Mechanism, Techniques and Durability

  • Manuja N1,*,
  • Nagpal R1
  • Pandit IK1

1Department of Paediatric Dentistry, Kothiwal Dental College, Moradabad, Uttar Pradesh, India

2Department of Paediatric Dentistry, DAV(c) Dental College, Yamunanagar, Haryana, India.

DOI: 10.17796/jcpd.36.3.68805rl1r037m063 Vol.36,Issue 3,May 2012 pp.223-234

Published: 01 May 2012

*Corresponding Author(s): Manuja N E-mail: naveenmanuja@yahoo.com

Abstract

Contemporary dental adhesives show favorable immediate results in terms of bonding effectiveness. However, the durability of resin-dentin bonds is their major problem. It appears that simplification of adhesive techniques is rather detrimental to the long term stability of resin-tooth interface. The hydrostatic pulpal pressure, the dentinal fluid flow and the increased dentinal wetness in vital dentin can affect the intimate interaction of certain dentin adhesives with dentinal tissue. Bond degradation occurs via water sorption, hydrolysis of ester linkages of methacrylate resins, and activation of endogenous dentin matrix metalloproteinases. The three-step etch-and-rinse adhesives still remain the gold standard in terms of durability. This review discusses the fundamental process of adhesion to enamel and dentin with different adhesive techniques, factors affecting the long term bonding performance of modern adhesives and addresses the current perspectives for improving bond durability.

Keywords

Adhesion, resin-dentin interface, hydrophilicity, durability.

Cite and Share

Manuja N,Nagpal R,Pandit IK. Dental Adhesion: Mechanism, Techniques and Durability. Journal of Clinical Pediatric Dentistry. 2012. 36(3);223-234.

References

1. Inoue S, Vargas MA, Van Meerbeek B, Abe Y, Yoshida Y, Lambrechts P, et al. Micro-tensile bond strength of eleven modern adhesives to dentin. J Adhes Dent, 3: 237–246, 2001.

2. Van Dijken JW. Clinical evaluation of three adhesive systems in class V non-carious lesions. Dent Mater, 16: 285–291, 2000.

3. Brackett WW, Covey DA, St-Germain HA Jr. One-year clinical performance of a self-etching adhesive in class V resin composites cured by two methods. Oper Dent, 27: 218–222, 2002.

4. Lopes GC, Baratieri LN, de Andrada MA, Vieira LC. Dental adhesion: Present state of the art and future perspectives. Quint Inter, 33(3): 213–224, 2002.

5. Roberson TM, Heymann HO, Swift EJ. Sturdevant’s Art and Science of Operative Dentistry. 4th Edition, Mosby; 237–261, 2002.

6. Terkla LG, Brown AC, Hainisch AP, Mitchem JC. Testing sealing properties of restorative materials against moist dentin. J Dent Res, 66: 1758–1764, 1987.

7. Van Hassel HJ. Physiology of the human dental pulp. Oral Surg Oral Med Oral Pathol, 32: 126–134, 1971.

8. Garberoglio R, Brannstrom M. Scanning electron microscopic investigation of human dentinal tubules. Arch Oral Biol, 21: 355–362, 1976.

9. Marchetti C, Piacentini C, Menghini P. Morphometric computerized analysis on the dentinal tubules and the collagen fibers in the dentine of human permanent teeth. Bull Group Int Rech Sci Stomatol Odontol, 35: 125–129, 1992.

10. Pashley DH. Dentin: a dynamic substrate-a review. Scan Microsc, 3:161–176, 1989.

11. Pashley DH, Ciucchi B, Sano H, et al. Bond strength versus dentine structure: a modeling approach. Arch Oral Biol, 40: 1109–1118, 1995.

12. Merchant VA, Livingston MJ, Pashley DH. Dentin permeability: comparison of diffusion with filtration. J Dent Res, 56: 1161–1164, 1977.

13. Richardson D, Tao L, Pashley DH. Dentin permeability: effects of crown preparation. Int J Prostho, 4: 219–225, 1991.

14. Pashley DH, Andringa HJ, Derkson GD, et al. Regional variability in the permeability of human dentine. Arch Oral Biol, 32: 519–523, 1987.

15. Maroli S, Khea SC, Krell KV. Regional variation in permeability of young dentin. Oper Dent, 17: 93–100, 1992.

16. Pashley EL, Talmann R, Horner JA, et al. Permeability of normal versus carious dentine. Endod Dent Traumatol, 7: 207–211, 1991.

17. Pashley DH, Livingston MJ, Greenhill JD. Regional resistances to fluid flow in human dentine, in vitro. Arch Oral Biol, 23: 807–810, 1978.

18. Van Meerbeek B, Vargas M, Inoue S, Yoshida Y, Peumans M, Lambrechts P, Vanherle G. Adhesives and cements to promote preservation dentistry. Oper Dent, (Supplement 6):119–144, 2001.

19. Van Meerbeek B, De Munck J, Yoshida Y, et al. Buonocore Memorial Lecture. Adhesion to enamel and dentin: Current status and future challenges. Oper Dent, 28: 215–235, 2003.

20. Koshiro K, Sidhu SK, Inoue S, Ikeda T & Sano H. New concept of resin-dentin interfacial adhesion: The nanointeraction zone. J Biomed Mater Res Part B Appl Biomater, 77(2): 401–408, 2006.

21. Perdigao J, Lambrechts P, Van Meerbeek B, Tome AR, Vanherle G, Lopes AB. Morphological field emission-SEM study of the effect of six phosphoric acid etching agents on human dentin. Dent Mater, 12: 262–271, 1996.

22. Nakabayashi N, Kojima K, Masuhara E. The promotion of adhesion by the infiltration of monomers into tooth substrates. J Biomed Mater Res, 16: 265–273, 1982.

23. Hannig M, Bock H, Bott B, Hoth-Hanning W. Intercrystallite nanoretention of self-etching adhesives at enamel imaged by transmission electron microscopy. Eur J Oral Sci, 110: 464–470, 2002.

24. Hanning M, Bock H, Bott B, Hoth-Hanning W. Self-etching primer vs phosphoric acid: an alternative concept for composite to enamel bonding. Oper Dent, 24; 172–180, 1999.

25. Hayakawa T, Kikutaka K, Nemoto K. Influence of self-etching primer treatment on the adhesion of resin composite to polished dentin and enamel. Dent Mater, 14(2): 99–105, 1998.

26. Perdiago J, Lopes L, Lambrechts P, Leitao J, Van Meerbeet B, Vanherle G. Effects of self-etching primer on enamel shear bond strengths and SEM morphology. Am J Dent 10(3): 141–146, 1997.

27. Pashley DH and Tay FR. Agressiveness of contemporary self-etching adhesives. Part 2: etching effects on unground enamel. Dent Mater, 17(5): 430–444, 2001.

28. Kanemura N, Sano H, Tagami J. Tensile bond strength to and SEM of ground and intact enamel surfaces. J Dent, 27(7): 523–530, 1999.

29. Breschi L, Gobbi P & Falconi M. Ultra-morphology of self-etching adhesives on ground enamel: A high resolution SEM study. A J Dent, 16: 57A–62A, 2003

30. Brackett WW, Ito S, Nishitani Y, Haisch LD, Pashley DH. The microtensile bond strength of self-etching adhesives to ground enamel. Oper Dent, 31: 332–337, 2006.

31. Watanabe T, Tsubota K, Takamizawa T, Kurokawa H, Rikuta A, Ando S, et al. Effect of prior acid etching on bonding durability of singlestep adhesives. Oper Dent, 33: 426–433, 2008.

32. Yoshida Y, Nagakane K, Fukuda R, Nakayama Y, Okazaki M, Shintani H, Inoue S, et al. Comparative study on adhesive performance of functional monomers. J Dent Res, 83(6): 454–458, 2004.

33. Pashley DH, Ciucchi B, Sano H, Horner JA. Permeability of dentin to adhesive agents. Quint Inter, 24: 618–631, 1993.

34. Kanca J. Resin bonding to wet substrate I: Bonding to dentin. Quint Inter, 23(1): 39–41, 1992.

35. Abate PF, Rodriguez VI, Macchi RL. Evaporation of solvent in onebottle adhesives. J Dent, 28(6): 437–440, 2000.

36. Tay FR, Gwinnett AJ, Pang KM, Wei SH. Resin permeation into acidconditioned, moist, and dry dentin: A paradigm using water-free adhesive primers. J Dent Res 75(4): 1034–1044, 1996.

37. Van Meerbeek B, Yoshida Y, Lambrechts P, Vanherle G, Duke ES, Eick JD, Robinson SJ. A TEM study of two water-based adhesive systems bonded to dry and wet dentin. J Dent Res, 77(1): 50–59, 1998.

38. Kanca J. Effect of resin primer solvents and surface wetness on resin composite bond strength to dentin. Am J Dent, 5(4): 213–215, 1992.

39. Kanca J. Improving bond strength through acid etching of dentin and bonding to wet dentin surfaces. J Am Dent Assoc, 123(9): 35–43, 1992.

40. Gwinnett AJ. Moist versus dry dentin: Its effect on shear bond strength. Am J Dent, 5(3): 127–129, 1992.

41. Jacobsen T, Söderhold KJ. Some effects of water on dentin bonding. Dent Mater, 11(2): 1 32–136, 1995.

42. Asmussen E, Peutzfeldt A. The influence of relative humidity on the effect of dentin bonding systems. J Adhes Dent, 3(2): 123–127, 2001.

43. Perdigão J, Frankenberger R. Effect of solvent and rewetting time on dentin adhesion. Quint Int, 32(5): 385–390, 2001.

44. Fogel HM, Marshall FJ, Pashley DH. Effects of distance from the pulp and thickness on the hydraulic conductance of human radicular dentin. J Dent Res, 67(11): 1381–1385, 1988.

45. Ozok AR, Wu MK, Wesselink PR. Comparison of the in vitro permeability of human dentine according to the dentinal region and the composition of the simulated dentinal fluid. J Dent, 30(2–3): 107–111, 2002.

46. Daculsi G, LeGeros RZ, Jean A, Kerebel B. Possible physico-chemical processes in human dentin caries. J Dent Res, 66(8): 1356–1359, 1987.

47. Schüpbach P, Lutz F, Guggenheim B. Human root caries: histopathology of arrested lesions. Caries Res, 26(3): 153–164, 1992.

48. Itthagarun A, Tay FR. Self-contamination of deep dentin by dentin fluid. Am J Dent, 13(4): 195–200, 2000.

49. Miyazaki M, Sato M, Onose H. Durability of enamel bond strength of simplified bonding systems. Oper Dent, 25: 75–80, 2000.

50. Bastioli C, Romano G, Migliaresi C. Water sorption and mechanical properties of dental composites. Biomater, 11: 219–223, 1990.

51. Eliades G, Vougiouklakis G, Palaghias G. Heterogeneous distribution of single-bottle adhesive monomers in the resin-dentin interdiffusion zone. Dent Mater, 17: 277–283, 2001.

52. Spencer P, Wang Y. Adhesive phase separation at the dentin interface under wet bonding conditions. J Biomed Mater Res, 62: 447–56, 2002.

53. Tay FR, Pashley DH, Yoshiyama M. Two modes of nanoleakage expression in single-step adhesives. J Dent Res, 81: 472–476, 2002.

54. Ferrari M, Tay FR. Technique sensitivity in bonding to vital acidetched dentin. Oper Dent, 28: 3–8, 2003.

55. Tay FR, Pashley DH, Yiu CK, Sanares AM, Wei SH. Factors contributing to the incompatibility between simplified-step adhesives and chemically-cured or dual-cured composites. Part1. Single-step selfetching adhesive. J Adhes Dent, 5: 27–40, 2003.

56. Nyunt MM, Imai Y. Adhesion to dentin with resin using sulfinic acid initiator system Dent Mater J, 15: 175-182, 1996.

57. Tay FR, Pashley DH, Have dentin adhesives become too hydrophilic? J Can Dent Assoc, 69: 726–731, 2003.

58. De Munck J, Van Landuyt K, Peumans M, Poitevin A, LambrechtsP, Braem M, Van Meerbeek B. A Critical Review of the Durability of Adhesion to Tooth Tissue: Methods and Results. J Dent Res, 84(2): 118–132, 2005.

59. Koshiro K, Inoue S, Sano H, De Munck J, Van Meerbeek B. In vivo degradation of resin-dentin bonds produced by a self-etch and an etchand-rinse adhesives. Eur J Oral Sci, 113: 341–348, 2005.

60. Ito S, Hashimoto M, Wadgaonkar B, Svizero N, Carvilho RM, Yiu C, et al. Effects of resin hydrophilicity on water sorption and changes in modulus of elasticity. Biomater, 26: 6449–6459, 2005.

61. Hashimoto M, Tay FR, Ito S, Sano H, Kaga M, Pashley DH. Permeability of adhesive resin films. J Biomed Mater Res Part B Appl Biomater, 74: 699–705, 2005.

62. Hashimoto M, Ohno H, Kaga M, Sano H, Endo K, Oguchi H. The extent to which resin can infiltrate dentin by acetone-based adhesives. J Dent Res, 81(1): 74–78, 2002.

63. Pashley DH, Tay FR, Yiu C, Hashimoto M, Breschi L, Carvalho RM, et al. Collagen degradation by host-derived enzymes during aging. J Dent Res, 83: 216–21, 2004.

64. Mazzoni A, Mannello F, Tay FR, Tonti GA, Papa S, Mazzotti G, et al. Zymographic analysis and characterization of MMP-2 and -9 forms in human sound dentin. J Dent Res, 86: 436–40, 2007.

65. Sulkala M, Larmas M, Sorsa T, Salo T, Tjaderhane L. The localization of matrix metalloproteinase-20 (MMP-20, anamelysin) in mature human teeth. J Dent Res, 81: 603–608, 2002.

66. Sulkala M, Tervahartiala T, Sorsa T, Larmas M, Salo T, Tjaderhane L. Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin. Arch Oral Biol, 52: 121–127, 2007.

67. Bourd-Boittin K, Fridman R, Fanchon S, Septier D, Goldberg M, Menashi S. Matrix metalloproteinase inhibition impairs the processing, formation and mineralization of dental tissues during mouse molar development. Experiment Cell Res, 304: 493–505, 2005.

68. Tervahartiala T, Larjava H, Sorsa T, Uittol VJ, Larmas M, Salol T. The activation and function of host matrix metalloproteinase in dentin matrix breakdown in caries lesions. J Dent Res, 77:1622–1629, 1998.

69. Mazzoni A, Pashley DH, Nishitani Y, Breschi L, Mannello F, Tjaderhane L, et al. Reactivation of inactivated endogenous proteolytic activities in phosphoric acid-etched dentine by etch-and-rinse adhesives. Biomater, 27: 4470–4476, 2006.

70. Nishitani Y, Yoshiyama M, Wadgaonkar B, Breschi L, Mannello F, Mazzoni A, et al.Activation of gelatinolytic/collegenolytic activity in dentin by self-etching adhesives. Eur J Oral Sci, 114:160–166, 2006.

71. Tay FR, Pashley DH, Loushine RJ, Weller RN, Monticelli F, Osorio R. Self-etching adhesives increase collagenolytic activity in radicular dentin. J Endod, 32: 862–868, 2006.

72. Zhang S, Kern M. The Role of Dentinal Host-derived Matrix Metalloproteinases in Reducing Dentin Bonding of Resin Adhesives. Int J Oral Sci, 1(4): 163–176, 2009 .

73. Oliveira SS, Marshall SJ, Habelitz S, Gansky SA, Wilson RS, Marshall GW Jr. The effect of a self- etching primer on the continuous demineralization of dentin. Eur J Oral Sci, 112(4): 376–383, 2004.

74. Wang Y, Spencer P. Hybridization efficiency of the adhesive/dentin interface with wet bonding. J Dent Res, 82(2): 141–145, 2003.

75. De Munck J, Van Meerbeek B, Yoshida Y, Inoue S, Vargas M, Suzuki K, et al. Four-year water degradation of total-etch adhesives bonded to dentin. J Dent Res, 82(2): 136–140, 2003.

76. Breschi L, Mazzoni A, Ruggeri A, Cadenaro M, Di Lenarda R, Dorigo E. Dental adhesion review: Aging and stability of the bonded interface. Dent Mater, 24: 90–101, 2008.

77. Gendron R, Grenier D, Sorsa T, Mayrand D. Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine. Clinical and Diagnostic Lab Immunol, 6(3): 437–439, 1999.

78. Breschi L, Mazzoni A, Nato F, Carrilho M, Visintini E, Tjaderhane L, Ruggeri Jr A, Tay FR. Chlorhexidine stabilizes the adhesive interface: a 2-year in vitro study. Dent Mater, 26: 320–325, 2010.

79. Brackett MG, Tay FR, Brackett WW, Dib A, Dipp FA, Mai S, Pashley DH. In vivo chlorhexidine stabilization of hybrid layers of an acetonebased dentin adhesive. Oper Dent, 34(4); 379–383, 2009.

80. Komori PCP, Pashley DH, Tjaderhane L, Breschi L, Mazzoni A, de Goes MF, Wang L , Carrilho MR. Effect of 2% chlorhexidine digluconate on bond strength to normal versus caries-affected dentin. Oper Dent, 34(2); 157–165, 2009.

81. Stanislawczuk R, Amaral RC, Zander-Grande C, Gagler D, Reis A, Loguercio AD. Chlorhexidine-containing acid conditioner preserves the longevity of resin-dentin bonds. Oper Dent, 34(4); 481–490, 2009.

82. Zhou J, Tan J, Chen L, Li D, Tan Y. The incorporation of chlorhexidine in a two-step self-etching adhesive preserves dentin bond in vitro. J Dent, 37: 807–812, 2009.

83. Sorsa T, Tjaderhane L, Konttinen YT, Lauhio A, Salo T, Lee HM, Golub LM, Brown DL, Mantyla P. Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Annals Med, 38(5): 306–321, 2006.

84. Hannas AR, Pereira JC, Granjeiro JM , Tjaderhane L. The role of matrix metalloproteinases in the oral environment. Acta Odontologica Scandinavica, 65(1): 1–13, 2007.

85. Hjeljord LG, Rolla G, Bonesvoll P. Chlorhexidine-protein interactions. J Periodon Res, 12(supplement): 11–16, 1973.

86. Breschi L, Martin P, Mazzoni A, Nato F, Carrilho M, Tjaderhane L, et al. Use of a specific MMP-inhibitor (galardin) for preservation of hybrid layer. Dent Mater, 26: 571–578, 2010.

87. Golub LM, Sorsa T, Lee HM, Ciancio S, Sorbi D, Ramamurthy NS, et al. Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva. J Clin Periodontol, 22(2): 100–109, 1995.

88. Golub LM, Lee HM, Ryan ME, Giannobile WV, Payne J, Sorsa T. Tetracyclines inhibit connective tissue breakdown by multiple nonantimicrobial mechanisms. Adv Dent Res, 12(2): 12–26, 1998.

89. Yamauchi M. Collagen biochemistry: An overview. In: Phillips GO, editor. Advances in Tissue Banking, Vol 6. New Jersey. World Scientific; 455–500, 2002.

90. Yamauchi M, Shiiba M. Lysine hydroxylation and crosslinking of collagen. Methods Mol Biol, 194:277–290, 2002.

91. Cheung DT, Tong D, Perelman N, Ertl D, Nimni ME. Mechanism of crosslinking of proteins by glutaraldehyde. IV: In vitro and in vivo stabilityof a crosslinked collagen matrix. Connect Tissue Res, 25: 27–34, 1990.

92. Han B, Jaurequi J, Tang BW, Nimni ME. Proanthocyanidin: a natural crosslinking reagent for stabilizing collagen matrices. J Biomed Mater Res A, 65: 118–124, 2003.

93. Bedran-Russo AKB, Pereira PNR, Duarte WR, Drummond JL, Yamauchi M. Application of crosslinkers to dentin enhances the ultimate tensile strength. J Biomed Mater Res B Appl Biomater, 80B: 268–272, 2007.

94. Joshi SS, Kuszynski CA, Baghi D. The cellular and molecular basis of health benefits of grape seed proanthocyanidin extract. Curr Pharm Biotechnol, 2: 187–200, 2001.

95. Fine AM. Oligomeric proanthocyanidin complexes: History, structure, and phytopharmaceutical applications. Altern Med Rev, 5: 144–151, 2000.

96. Cowan MM. Plant products as antimicrobial agents. Clin Microbiol Rev, 12: 564–582, 1999.

97. Scalbert A, Deprez S, Mila I, Albrecht AM, Huneau JF, Rabot S. Proanthocyanidins and human health: systemic effects and local effects in the gut. Biofactors, 13: 115–120, 2000.

98. Teissedre PL, Frankel EN, Waterhouse AL, Peleg H, German JB. Inhibition of in vitro human LDL oxidation by phenolic antioxidants from grapes and wines. J Sci Food Agriculture, 70: 55–61, 1996.

99. Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radicals Bio Med, 20: 933–956, 1996.

100. Al-Ammar A, Drummond JL, Bedran-Russo AKB. The use of collegen cross-linking agents to enhance dentin bond strength. J Biomed Mater Res B Appl Biomater, 91(1): 419–424, 2009.

101. Castellan CS, Pereira PNR, Viana G, Chen S, Pauli GF, Bedran-Russo AKB. Solubility study of phytochemical cross-linking agents on dentin stiffness. J Dent, 38: 431–436, 2010.

102. Green B, Yao X, Ganguly A, Xu C, Dudevich V, Walker MP, Wang Y. Grape seed proanthocyanidins increase collagen biodegradation resistance in the dentin/adhesive interface when included in an adhesive. J Dent, 38(11): 908–915, 2010.

103. Brackett WW, Ito S, Tay FR, Haisch LD, Pashley DH. Microtensile dentin bond strength of self-etching resins: Effect of a hydrophobic layer. Oper Dent, 30: 733–738, 2005.

104. Reis A, Albuquerque M, Pegoraro M, Mattei G, Bauer JR, Grande RH, et al. Can the durability of one-step self-etch adhesives be improved by double application or by an extra layer of hydrophobic resin? J Dent, 33: 309–315, 2008.

105. Albuquerque M, Pegoraro M, Mattei G, Reis A, Loguercio AD. Effect of double-application or the application of a hydrophobic layer for improved efficacy of one-step self-etch systems in enamel and dentin. Oper Dent, 33: 564–570, 2008.

106. Tay FR, Pashley DH, Suh BI, Carvalho RM, Itthagarum. Single-step adhesives are permeable membranes. J Dent, 30: 371–382, 2008.

107. Choi KK, Condon JR, Ferracane JL. The effects of adhesive thickness on polymerization contraction stress of composite. J Dent Res, 79: 812–817, 2000.

108. Lodovici E, Reis A, Geraldeli S, Ferracane JL, Ballester RY, Filho LE. Does adhesive thickness affect resin-dentin bond strength after thermal/load cycling? Oper Dent, 34: 58–64, 2009.

109. Brackett MG, Brackett WW, Haisch LD. Microleakage of class V resin composites placed using self-etching resins: Effect of prior enamel etching. Quint Inter, 37: 109–113, 2006.

110. Van Landuyt KL, Kanumilli P, De Munck J, Peumans M, Lambrechts P, Van Meerbeek B. Bond strength of a mild self-etch adhesive with and without prior acid-etching. J Dent, 34: 77–85, 2006.

111. Van Meerbeek B, Kanumilli P, De Munck J, Van Landuyt KL, Lambrechts P, Peumans M. A randomized controlled study evaluating the effectiveness of a two-step self-etch adhesive with and without selective phosphoric-acid etching of enamel. Dent Mater, 21: 375–383, 2005.

112. Luhrs AK, Guhr S, Schilke R, Borchers L, Geurtsen W, Gunay H. Shear bond strength of self- etch adhesives to enamel with additional phosphoric acid etching. Oper Dent, 33: 155–162, 2008.

113. Ermis RB, Temel UB, Celik EU, Kam O. Clinical performance of a two-step self-etch adhesive with additional enamel etching in class III cavities. Oper Dent, 35: 147–155, 2010.

114. Khosravi K, Ataei E, Mousavi M, Khodaeian N. Effect of phosphoric acid etching of enamel margins on the microleakage of a simplified all-in-one and a self-etch adhesive system. Oper Dent, 34: 531–536, 2009.

115. Elkassas D, Taher HA, Elsahn N, Hafez R, El-Badrawy W. Effect of number of applications of acetone-based adhesives on microtensile bond strength and the hybrid layer. Oper Dent, 34(6): 688–696, 2009.

116. Reis A, Pellizzaro A, Bianco KD. Impact of adhesive application to wet and dry dentin on long-term resin dentin bond strength. Oper Dent, 32(4): 380–387, 2007.

117. Tewari S, Goel A. Effect of placement agitation and drying time on dentin shear bond strength: an in vivo study. Oper Dent, 34(5): 524–530, 2009.

118. Amaral RC, Stanislawczuk R, Zander-Grande C, Gagler D, Reis A, Loguercio AD. Bond strength and quality of the hybrid layer of onestep self-etch adhesives applied with agitation on dentin. Oper Dent, 35(2): 211–219, 2010.

119. Garcia FCP, Almeida JCF, Osorio R, Carvalho RM, Toledano M. Influence of drying time and temperature on bond strength of contemporary adhesives to dentine. J Dent, 37: 315–320, 2009.

120. Chiba Y, Yamaguchi K, Miyazaki M, Tsubota K, Takamizawa T, Moore BK. Effect of air-drying time of single application self-etch adhesives on dentin bond strength. Oper Dent, 31(2): 233–239, 2006.

121. Saboia Vde PA, Pimenta LA, Ambrosano GM. Effect of collagen removal on microleakage of resin composite restorations. Oper Dent, 27(1): 38–43, 2002.

122. Montes MA, de Goes MF, Ambrosano GM, Durate RM, Sobrinho LC. The effect of collagen removal and the use of a low-viscosity resin liner on marginal adaptation of resin composite restorations with margins in dentin. Oper Dent, 28(4): 378–387, 2003.

123. Shinohara MS, Bedran-de-Castro AK, Amaral CM, Pimenta LA. The effect of sodium hypochlorite on microleakage of composite resin restorations using three adhesive systems. J Adhes Dent, 6(2): 123–127, 2004.

124. Nagpal R, Tewari S, Gupta R. Effect of various surface treatments on the microleakage and ultrastructure of resin-tooth interface. Oper Dent, 32: 116–123, 2007.

125. Pashley DH, Tay FR, Carvalho RM, Rueggeberg FA, et al. From dry bonding to water-wet bonding to ethanol-wet bonding. A review of the interactions between dentin matrix and solvated resins using a macromodel of the hybrid layer. Am J Dent, 20: 7–20, 2007.

126. Kim J, Gu L, Breschi L, Tjaderhane L, Choi KK, Pashley DH, Tay FR. Implication of ethanol wet-bonding in hybrid layer remineralization. J Dent Res, 89: 575–580, 2010.

127. Sadek FT, Mazzoni A, Breschi L, Tay FR, Braga RR. Six-month evaluation of adhesives interface created by a hydrophobic adhesive to acid-etched ethanol-wet bonded dentine with simplified dehydration protocols. J Dent, 38: 276–283, 2010.

128. Osorio E, Toledano M, Aguilera FS, Tay FR, Osorio R. Ethanol wetbonding technique sensivity assesses by AFM. J Dent Res, 89: 1264–1269, 2010.

129. Tay FR, Pashley DH, Kapur RR, Carrilho MR, Hur YB, Garrett LV, et al. Bonding BisGMA to dentin-a proof-of-concept for hydrophobic dentin bonding. J Dent Res, 86: 1034–1039, 2007.

130. Hosaka K, Nishitani Y, Tagami J, Yoshiyama M, Brackett WW, Agee KA, Tay FR, Pashley DH. Durability of resin-dentin bonds water vs. ethanol-saturated dentin. J Dent Res, 88: 146–151, 2009.

131. Tay FR, Pashley DH. Guided tissue remineralisation of partially deminralised human dentine. Biomater, 29: 1127–1137, 2008.

132. He G, Gajjerman S, Schultz D, Cookson D, Qin C, Butler WT, et al. Spatially and temporally controlled biomineralization is facilitated by interaction between self-assembled dentin matrix protein 1 and calcium phosphate nuclei in solution. Biochem, 44: 16140–16148, 2005.

133. Gajjerman S, Narayann K, Hao J, Qin C, George A. Matrix macromolecules in hard tissues control the nucleation and hierarchical assembly of hydroxyapatite. J Biol Chem, 282: 1193–1204, 2007.

134. Tay FR, Pashley DH. Biomimetic remineralization of resin-bonded acid etched dentin. J Dent Res, 88: 719–724, 2009.

135. Mai S, Kim YK, Kim J, Yiu CKY, Ling J, Pashley DH, Tay FR. In vitro remineralization of severely compromised bonded dentin. J Dent Res, 89: 405–410, 2010.

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Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 1.8 (2023) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

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