Lead Exposure and its Relation to Dental Caries in Children

Environmental pollution is a significant health hazard and is mainly caused by commercialization. The etiology of dental caries is multifactorial and one such factor is exposure to trace element such as lead. Aim: Hence, the present study was carried out to find out the correlation between the levels of lead in the enamel, saliva and dental caries in children. Method: 90 children aged 5 years consisting of both genders from different kindergartens along Coastal Karnataka were included in the study. The selected children were divided into 3 groups as; control group, early childhood caries (ECC) group and severe-ECC (S-ECC) group respectively. Enamel and salivary lead level was assessed by using graphite atomic absorption spectrophotometry. Results: Mean enamel lead levels in the control, ECC and S-ECC group were 47.7, 85.45 and 90.43 ppm respectively and mean salivary lead levels were 0.23, 1.7 and 1.77 ppm respectively which was statistically very highly significant (p < 0.001) with no gender predilection. There was a positive correlation seen between the enamel and the salivary lead levels (p ≯ 0.05).Conclusion: The enamel and the saliva of all the children had measurable amounts of lead and its levels increased with increase in severity of dental caries proving the cariogenic potential of lead. A positive correlation was seen between the enamel and the salivary lead levels.

Enamel lead, salivary lead, dental caries, deciduous teeth, primary teeth

1. Llobet JM, Falco G, Casas C, Texido A, and Domingo JL. Concentrations of Arsenic, Cadmium, Mercury, and Lead in common foods and estimated daily intake by children, adolescents, adults, and seniors citizens of Catal-onia, Spain. J. Agric. Food Chem. 51:838-842, 2003.

2. Rifai N et al. Incidence of lead poisoning in young children from inner-city, sub-urban, and rural communities. Therap Drug Monitor 15:71-4, 1993.

3. Al-Mahroos F, Al-Saleh FS. Lead levels in deciduous teeth of children in Bahrain. Ann Trop Paediatr 17:147-54, 1997.

4. Centers for Disease Control and Prevention. Preventing Lead Poisoning in Young Children: A Statement by the Centers for Disease Control, October 1991. Atlanta, GA: US Dept of Health and Human Services, 1991.

5. Hernandez-Guerrero JC, Jimenez-Farfan MD, Belmont R, Ledes-ma-Montes C, Baez A. Lead levels in primary teeth of children living in Mexico city. Int J Paediatr Dent 14:175-81; 2004.

6. Balwant Rai, Simmi Kharb, Anand SC. Saliva as a Diagnostic Tool in Medical Science: a Review Study. Med. Dent. Sci., 2(1): 9-12, 2008.

7. Slavkin HC. Toward molecularly based diagnostics for the oral cavity. JADA 129: 1138-1143.

8. Brudevold F, Aasenden R, Srinivasan BN , Bakhos Y. Lead in enamel and saliva, dental caries and the use of enamel biopsies for measuring past exposure to lead. Journal of dental research 56(10):1165-1171, 1977.

9. Bowen WH. Exposure to metal ions and susceptibility to dental caries. Journal of dental education 65(10):1046-1053, 2001.

10. Simons TJ. Cellular interactions between lead and calcium. Br Med Bull 42:431-4, 1986.

11. World Health Organization. Oral health surveys: basic methods. 4th ed. Geneva: WHO; 1997.

12. Definition of early childhood caries. American academy of pediatric dentistry council on clinical affairs. Pediatric dentistry reference manual 2007.

13. Gomes VE, Wada RS, Cury JA, Luz MD. Lead level, enamel defects and dental caries in deciduous teeth. Rev Saude Publica 38(5):1-6; 2004.

14. Fiske CH, Subbarow Y. The calorimetric determination of phosphorous. J Biol Chem 66:375-400; 1925.

15. FDI core working group. IDJ 42:291-304, 1992.

16. Feldman W, Randel P. Screening children for lead exposure in Canada. In: Goldbloom RB (ed.). Canadian task force on the periodic health exam-ination. Canadian guide to clinical preventive health care. Ottawa: Health Canada, 268-288, 1994.

17. Gil F, Facio A, Villanueva E, Pérez ML, Tojo R, Gil A. The association of tooth content with dental health factors. Sci Total Environ 192:183-91; 1996.

18. Cleymaet R, Retief DH, Quartier E, Slop D, Coomans D, Michotte Y. A comparative study of lead and cadmium content of surface enamel of Belgian and Kenyan children. Science of The Total Environment 104:175-89, 1991.

19. Chatman T, Wilson DJ. Lead levels in human deciduous teeth in Tennessee. Environ Lett. 1975; 8(2):173-83.