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Original Research

Open Access

Relationship between Disk Position and Degenerative Bone Changes in Temporomandibular Joints of Young Subjects with TMD. An MRI Study

  • Moncada G1,*,
  • Cortés D1
  • Millas R1
  • Marholz C1

1Universidad Mayor, Dental School, Alameda 2013, Santiago, RM, Chile.

DOI: 10.17796/jcpd.38.3.w43m8474433n7ur2 Vol.38,Issue 3,April 2014 pp.269-276

Published: 01 April 2014

*Corresponding Author(s): Moncada G E-mail: gmoncada@adsl.tie.cl

Abstract

This study determines the frequency and relationship between disk position and degenerative bone changes in temporomandibular joints in children and adolescent patients with internal derangement. Study design: TMJ, MRI of 88 patients were analyzed (average age: 14.7 years-old, range age: 10-18 years-old), female n=65 (73.9%) and male n=23 (26.1%). Images obtained were used to determine the frequency of disk position, joint effusion (JE) and degenerative bone changes (OA). Images were assessed by a calibrated radiologist (Kappa=0.82). Results: No significant association was found between disk displacement with reduction and degenerative bone changes (Chi2=9.894; OR= 0.375; p=0.0017), nor disk without displacement (Chi2=9.448; OR= 0.223; p=0.0021). A significant association was found between disk displacement without reduction and degenerative bone changes (Chi2=30.951; OR=6.304; p=0.0001). Conclusions: There is a significant association between disk displacement without reduction and degenerative bone changes (p=0.0001) in children and adolescent patients with TMD.

Keywords

TMJ, TMD, MRI, TMJ Disk, degenerative bone disease, children, internal derangement.

Cite and Share

Moncada G,Cortés D,Millas R,Marholz C. Relationship between Disk Position and Degenerative Bone Changes in Temporomandibular Joints of Young Subjects with TMD. An MRI Study. Journal of Clinical Pediatric Dentistry. 2014. 38(3);269-276.

References

1. Michelotti A, Iodice G. The role of orthodontics in temporomandibulardisorders.J Oral Rehabil.;37(6):411-29. 2010.

2. Rossetti L, Rossetti P, Rodriguez P, Pereira C. Association Between Sleep Bruxism and Temporomandibular Disorders: A Polysomnographic Pilot Study. Cranio;26(1):16-23. 2008.

3. Okeson JP, de Leeuw R. Differential diagnosis of temporomandibular disorders and other orofacial pain disorders. Dent Clin North Am; 55(1):105-20. 2011.

4. Cooper B, Kleinberg I. Establishment of a Temporomandibular Physiological State with Neuromuscular Orthosis Treatment Affects Reduction of TMD Symptoms in 313 Patients. Cranio;26(2):104-117. 2008.

5. Stegenga B, De Bont LGM, Boering G. A proposed classification of Temporomandibular disorders base on synovial joint pathology. Cranio;7:107-118. 1989.

6. Hirsch C, Hoffmann J, Türp JC. Are temporomandibular disorder symptoms and diagnoses associated with pubertal development in adolescents? An epidemiological study. J Orofac Orthop; 73(1):6-8, 10-8. 2012.

7. Sener S, Akgünlü F. MRI Characteristics of anterior disk displacement with and without reduction. Dentomaxillofacial Radiology;33:245-252. 2004.

8. Campos MI, Campos PS, Cangussu MC, Guimarães RC, Line SR Analysis of magnetic resonance imaging characteristics and pain in temporomandibular joints with and without degenerative changes of the condyle. Int J Oral Maxillofac Surg.;37:529-34. 2008,

9. Cortese S, Oliver L, Biondi A. Determination of Range of Mandibular Movements in Children without Temporomandibular Disorders. Cranio; 25(3):200-205. 2007.

10. Cortes D, Exss E, Marholz C, Millas R, Moncada G. Association between disk position and degenerative bone changes of the temporomandibular joints: an imaging study in subjects with TMD. Cranio; 29(2):117-26. 2011.

11. Vierola A, Suominen AL, Ikavalko T, Lintu N, Lindi V, Lakka HM, Kellokoski J, Narhi M, Lakka TA. Clinical signs of temporomandibular disorders and various pain conditions among children 6 to 8 years of age: the PANIC study. J Orofac Pain; 26(1):17-25. 2012.

12. Hirsch C, Hoffmann J, Türp JC. Are temporomandibular disorder symptoms and diagnoses associated with pubertal development in adolescents? An epidemiological study. J Orofac Orthop; 73(1):6-8, 10-8. 2012.

13. Torii K. Longitudinal course of temporomandibular joint sounds in Japanese children and adolescents. Head Face Med; 27;7:17. 2011.

14. Tecco S, Crincoli V, Di Bisceglie B, Saccucci M, Macrĺ M, Polimeni A, Festa F. Signs and symptoms of temporomandibular joint disorders in Caucasian children and adolescents. Cranio ;29(1):71-9. 2011.

15. Köhler AA, Helkimo AN, Magnusson T, Hugoson A. Prevalence of symptoms and signs indicative of temporomandibular disorders in children and adolescents. A cross-sectional epidemiological investigation covering two decades. Eur Arch Paediatr Dent.;10. Suppl 1:16-25. 2009.

16. Ribeiro RF, Tallents RH, Katzberg RW, Murphy WC, Moss ME, Magalhaes AC, Tavano O. The prevalence of disk displacement in symptomatic and asymptomatic volunteers aged 6 to 25 years. J Orofac Pain.;11(1):37-47.1997.

17. Hans MG, Lieberman J, Goldberg J, Rozencwig G, Bellon E. A comparison of clinical examination history and magnetic resonance imaging for identifying orthodontic patients with temporomandibular joint disorders. Am J Orthod Dentofac Orthop;101:54-59. 1992.

18. Paesani D, Salas E, Martinez A, Isberg A. Prevalence of temporomandibular joint disk displacement in infant and young children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod;87:15-19.1999.

19. Kurita H, Kojima Y, Koike T, Kobayashi H, Kurashina K. Relationship between temporomandibular joint-related pain and morphological changes of the TMJ condyle in patients with temporomandibular disorders. Dentomaxilofacial Radiol; 33:329-333. 2004.

20. Güler N, Yatmaz H, Emlik D and Uckan S. Temporomandibular internal derangement: correlation of MRI findings with clinical symptoms of pain and joint sounds in patients with bruxism behaviour. Dentomaxillofacial Radiol;32:304-310. 2003.

21. Sener S, Yasar F, Yesilova E, Akgunlu F. Observer agreement in qualitative assessments of condylar position: Magnetic resonance imaging and transcranial radiography. DishekFakDerg ;18:265-273. 2009.

22. Stegenga B, de Bont L, van derKuijl B, Boering B. Classification of temporomandibular joint Osteoarthrosis and internal derangement. Part 1: Diagnosis significance of clinical and radiographic symptoms and signs. Cranio;10:96-117. 1992.

23. Stegenga B, de Bont L, Boering G. Osteoarthrosis as the cause of cranio mandibular pain and dysfunction. A unifying concept. J Oral Maxillofac Surg ; 47(3): 249-256. 1989.

24. Dijkgraaf L, de Bont L, Boering G, Liem R. Normal Cartilage Structure, Biochemistry and Metabolism: A review of the Literature. J Oral Maxilofacial Surg; 53: 924-929. 1995.

25. Dijkgraaf L, de Bont L, Boering G, Liem R. The structure, Biochemistry and metabolism of Osteoarthritis Cartilage: a review of the Literature. J Oral Maxilofacial Surg; 53:1182-1192.1995.

26. Tecco S, Crincoli V, Di Bisceglie B, Saccucci M, Macrĺ M, Polimeni A, Festa F. Signs and symptoms of temporomandibular joint disorders in Caucasian children and adolescents. Cranio; 29(1):71-9. 2011.

27. Pereira LJ, Pereira-Cenci T, Del BelCury AA, Pereira SM, Pereira AC, Ambosano GM, Gavião MB. Risk indicators of temporomandibular disorder incidences in early adolescence. Pediatr Dent.;32(4):324-8. 2010.

28. Mercuri LG. Osteoarthritis, osteoarthrosis, and idiopathic condylar resorption. Oral MaxillofacSurg Clin North Am.;20(2):169-83. 2008.

29. Moyaho-Bernal A, Lara-Muñoz M del C, Espinosa-De Santillana I, Etchegoyen G. Prevalence of signs and symptoms of temporomandibular disorders in children in the State of Puebla, Mexico, evaluated with the research diagnostic criteria for temporomandibular disorders (RDC/TMD). Acta Odontol Latinoam; 23(3):228-33. 2010.

30. Miamoto CB, Pereira LJ, Paiva SM, Pordeus IA, Ramos-Jorge ML, Marques LS.Prevalence and risk indicators of temporomandibular disorder signs and symptoms in a pediatric population with spastic cerebral palsy. J Clin Pediatr Dent ;35(3):259-63. 2011.

31. Pereira LJ, Pereira-Cenci T, Pereira SM, Cury AA, Ambrosano GM, Pereira AC, Gavião MB. Psychological factors and the incidence of temporomandibular disorders in early adolescence. Braz Oral Res ;23(2):155-60. 2009.

32. Von Korff M, Dworkin SF, Le Resche L, Kruger A. An epidemiologic comparison of pain complaints. Pain;32:173-83.1988.

33. Lipton JA, Ship JA, Larach-Robinson D. Estimated prevalence and distribution of reported orofacial pain in the USA. J Am Dent Assoc; 124:115-121.1993.

34. Milam SB, Aufdemorte TB, Sheridan PJ, Triplett RG, Van Sickels JE, Holt GR.Sexual dimorphism in the distribution of estrogen in receptors in the TMJ complex of the baboon. Oral Surg Oral Med Oral Pathol.;64:527-32.1987.

35. Wang W, Hayami T, Kapila S, Female hormone receptors are differentially expressed in mouse fibrocartilages. Osteoarthritis Cartilage. J Rheumatol;17(5):646-54. 2009.

36. Khalkhali-Ellis Z, Seftor EA, Nieva DR, Handa RJ, Price RH Jr, Kirschmann DA. Estrogen and progesterone regulation of human fibroblast-like synoviocyte function in vitro: implications in reumatismo arthritis. J Rheumatol; 27:1622-31. 2000.

37. Lee YJ, Lee EB, Kwon YE, Lee JJ, Cho WS, Kim HA. Effect of estrogen on the expression of matrix metalloproteinase (MMP)-1, MMP-3, and MMP-13 and tissue inhibitor of metalloproternase-1 in osteoarthritis chondrocytes. Rheumatol Int; 23:282-8. 2003.

38. Lu T, Achari Y, Rattner JB, Hart DA. Evidence that estrogen receptor beta enhances MMP-13 promoter activity in HIG-82 cells and that this enhancement can be influenced by ligands an involves specific promoter sites. Biochem Cell Biol,85.326-36.2007.

39. Hashem G, Zhang Q, Hayami T, Chen J, Wang W, Kapila S. Relaxyn and beta-estradiol modulated targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis Res Ther;8(4):R98. 2006.

40. Johnson AB, Sohrabji F. Estrogen’s effects on central and circulating inmune cells vary with reproductive age. Neurobiol Aging; 26-1365-74.2005.

41. Talwar RM, Wong BS, Svoboda K, Harper RP. Effects of estrogen on chondrocyte proliferation and collagen synthesis in skeletally mature articular cartilage. J Oral Maxillofac Surg; 64:600-9. 2006.

42. Shimonovitz S, Hurwitz A, Hochner-Celnikier D, Dushnik M, Anteby E, Yagel S. Espressions of gelatinase B by trophoblast cells: down regulation by progesterone. Am J Obstet Gynecol;178:457-61. 1998.

43. Salamonsen LA, Wolley DE. Menstruation: induction by matrix matalloproteinases and inflammatory cells. J Reprod Inmunol; 44:1-27.1999.

44. Wang W, Hayami T, Kapila S. Estrogen/relaxin induce while progesterone represses MMPs expression in TMJ fibrochondrocytes. J Den Res;86-1279.2007.

45. Kapila S, Wang W, Uston K. Matrix metalloproteinase induction by relaxin causes cartilage matrix degradation in target synovial joints: Receptor Profiles Correlate with Matrix Turnover. Ann N Y Acad Sci. Apr;1160:322-8. 2009.

46. Artvinli LB, Kansu O. Trifid mandibular condyle: A case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod;95(2):251. 2003.

47. Cagirankaya LB, Hatipoglu MG. Trifid mandibular condyle: a case report. Cranio; 23(4):297-9. 2005.

48. Warhekar AM, Wanjari PV, Phulambrikar T. Unilateral trifid mandibular condyle: a case report. Cranio. ;29(1):80-4. 2011.

49. Nebbe B, Major PW, Prasad NG, Grace M, Kamelchuk LS. TMJ internal derangement and adolescent craniofacial morphology: A pilot study. Angle Orthod; 67(6):407-414.1997.

50. Keeling SD, McGorray S, Wheeler TT, King GJ. Risk factors associated with temporomandibular joint sounds in children 6 to 12 years of age. Am J Orthod Dentofac Orthop;105:279-87.1994.

51. Gazit E, Lieberman M, Eini R, Hirsch N, Serfaty V, Fuchs C, Lilos P. Prevalence of mandibular dysfunction in 10-18 year old Israeli schoolchildren. J Oral Rehabil;11(4):307-17. 1984.

52. Flores-Mir C, Nebbe B, Heo G, Major PW. Longitudinal study of temporomandibular joint disk status and craniofacial growth. Am J Orthod Dentofac Orthop.;130(3):324-30. 2006.

53. Brooks SL, Brand JW, Gibbs SJ, Hollender L, Lurie AG, Omnell KA, Westesson PL, White SC. Imaging of the temporomandibular joint: a position paper of the American Academy of Oral and Maxillofacial Radiology. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.;83(5):609-18. 1997.

54. Cirbus MT, Smilack MS, Beltran J, Simon DC. Magnetic resonance imaging in confirming internal derangement of the temporomandibular joint. J Prosthet Dent.;57(4):488-94. 1987.

55. Cevidanes LH, Hajati AK, Paniagua B, Lim PF, Walker DG, Palconet G, Nackley AG, Styner M, Ludlow JB, Zhu H, Phillips C. Quantification of condylar resorption in temporomandibular joint osteoarthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.;110(1):110-7. 2010.

56. Arnett GW, Milan SB, Gotlesman L. Progressive mandibular retrusion-idiopathic condylar resorption. Part I. Am J Orthod Dentofac Orthop;110:8- 15. 1996.

57. Dworkin SF, Leresche L. Research diagnosis criteria for temporomandibular disorders, review, criteria, examinations and specifications, critique. J Craniomandib Disord;6:301-355.1992.

58. Manfredini D, Bucci MB, Montagna F, Guarda-Nardini L. Temporomandibular disorders assessment: medico legal considerations in the evidencebased era. J Oral Rehabil;38:101-119.2011.

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