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Lidocaine versus Mepivacaine in Sedated Pediatric Dental Patients: Randomized, Prospective Clinical Study

  • Aylin Sipahi Çalış1
  • Esra Cagiran1
  • Candan Efeoglu1
  • Aslı Topaloglu Ak1,*,
  • Huseyın Koca1

1Ege University Faculty of Dentistry, Izmır, Turkey

DOI: 10.17796/jcpd.39.1.g12782873611827u Vol.39,Issue 1,January 2015 pp.74-78

Published: 01 January 2015

*Corresponding Author(s): Aslı Topaloglu Ak E-mail: aslitopaloglu@yahoo.com

Abstract

Dental anxiety is usually seen in the pediatric patients. specially in the case of minor oral surgical procedures and exodontia, cooperation of the patients and their families with the dentist will lead to superior treatment outcomes. Pain control is important in dentistry. The aim of this randomized prospective clinical study is to compare the local anaesthetic and haemodynamic effects of 2% lidocaine (Group 1) and 3% mepivacaine (Group 2) in sedated pediatric patients undergoing primary tooth extraction. Study design: 60 pediatric patients undergoing sedation for elective primary tooth extraction was prospectively included in the study in a randomized fashion. Inclusion and exlusion criteria were assigned. Patients were given premedication via oral route. Local anesthesia was achieved before extraction(s). Results: There were no significant differences between the groups in patient demographics, number of teeth extracted, duration of the operation and time from the end of the procedure to discharge (p≯0.05). FLACC pain scale scores were not statistically significant between the groups, except at 20 minutes post-operatively when the score is significantly lower in Group 2 (p=0.029). Conclusion: Prevention of pain during dental procedures can nurture the relationship of the patient and dentist. Tooth extraction under sedation in pediatric patients could be safe with both local anesthetics.

Keywords

Lidocaine, Mepivacaine, Sedation, Anxiety, children

Cite and Share

Aylin Sipahi Çalış,Esra Cagiran,Candan Efeoglu,Aslı Topaloglu Ak,Huseyın Koca. Lidocaine versus Mepivacaine in Sedated Pediatric Dental Patients: Randomized, Prospective Clinical Study. Journal of Clinical Pediatric Dentistry. 2015. 39(1);74-78.

References

1- Wilson S. Management of child patient behavior: quality of care, fearm and anxiety and the child patient. J Endod 39:73-77, 2013.

2-Erlandsson AL, Bäckman B, Stenström A, Stecksén-Blicks C. Conscious sedation by oral administration of midazolam in paediatric dental treatment. Swed Dent J 25:97-104, 2001.

3-Malamed SF: Clinical Action of Spesific Agents. In Malamed SF(ed):Handbook of Local Anesthesia, Vol 5(ed 5). St Louis, MO, Elsevier; 57-75, 2004.

4-Silva LC, Santos T , Santos J A, Maia M , Mendonça CG. Articaine versus lidocaine for third molar surgery: A randomized clinical study. Med Oral Patol Oral Cir Bucal 17:140-145, 2012.

5-Rebolledo AS, Molina ED, Aytes LB , Escoda CG. Comparative study of the anesthetic efficacy of 4% articaine versus 2% lidocaine in inferior alveolar nerve block during surgical extraction of impacted lower third molars Med Oral Patol Oral Cir Bucal 12:139-144, 2007.

6- Hawkins JM, Moore PA. Local anesthesia: advances in agents and techniques. Dent Clin North Am 46:719-732, 2002.

7- Porto G.G, Do Egito Vasconcelos B.C, Gomes A.C.A, Albert D. Evaluation of lidocaine and mepivacaine for inferior third molar surgery. Med Oral Patol Oral Cir Bucal 12:60-64, 2007.

8-Guideline on appropriate use of local anesthesia for pediatric dental patients. American Academy on Pediatric Dentistry Council on Clinical Affairs. Pediatr Dent 30:134-139, 2008.

9-Ramsay MA, Savege TM, Simpson BR, et al. Controlled sedation with alphaxalone-alphadolone. Br Med J. 2:656–659, 1974.

10-Babl FE, Crellin D, Cheng J, Sullivan TP, O’Sullivan R, Hutchinson A.The use of the faces, legs, activity, cry and consolability scale to assess procedural pain and distress in young children. Pediatr Emerg Care 28:1281- 1296, 2012.

11- Nathan JE, Venham LL, West MS, Werboff J. The effects of nitrous oxide on anxious young pediatric patients across sequential visits: A double-blind study. ASDC J Dent Child 55:220-230, 1988.

12- Malamed SF. Basic injection technique in local anesthesia. In: Handbook of Local Anesthesia. 5th ed. St. Louis, Mo: Mosby;159-69, 2004.

13- Fernieini EM, Bennett JD, Silverman DG, Halaszynski TM. Hemodynamic assessment of local anesthetic administration by laser Doppler flowmetry. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91:526-530, 2001.

14- Knoll-Köhler E, Frie A, Becker J, Ohlendor D. Changes in plasma epinephrine concentration after dental infiltration anesthesia with different doses of epinephrine . J Dent Res. 68:1098-1101, 1989.

15- Matsumura K, Miura K, Takata Y, Kurokawa H, Kajiyama M, Abe I, Fujishima M. Changes in blood pressure and heart rate variability during dental surgery. Am J Hypertens 11:1376-80, 1998.

16- Muzyka BC, Glick M. The hypertensive dental patient. JADA 128:1109-1120, 1997.

17- Little JW.The impact on dentistry of recent advances in the management of hypertension.Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:591-599, 2000.

18- Brand HS, Gortzak RA, Palmer-Bouva CC, Abraham RE, Abraham-In-pijn L.Cardiovascular and neuroendocrine responses during acute stress induced by different types of dental treatment. Int Dent J 45:45-48, 1995.

19- Ezmek B, Arslan A, Delilbaşı C, Sençift K. Comparison of hemodynamic effects of lidocaine, prilocaine and mepivacaine solutions without vasocon-strictor in hypertensive patients. J Appl Oral Sci. 18:354-359, 2010.

20- Porto GG, Vasconcelos B C, Gomes A C A , Albert D. Evaluation of lido-caine and mepivacaine for inferior third molar surgery. Med Oral Patol Oral Cir Bucal 12:60-64, 2007.

21- Masue T, Shimonaka H, Fukao I, Kasuya S, Kasuya Y, Dohi S.Oral high-dose midazolam premedication for infants and children undergoing cardio-vascular surgery. Paediatr Anaesth 13: 662-667, 2003.

22- Odabaş ME, Cınar C, Deveci C, Alaçam A. Comparison of the anesthetic efficacy of articaine and mepivacaine in pediatric patients: a randomized, double-blind study. Pediatr Dent.34:42-45, 2012.

23- Hinkley SA, Reader A, Beck M, Meyers WJ. An evaluation of 4% prilo-caine with 1:200,000 epinephrine and 2% mepivacaine with 1:20,000 levonordefrin compared with 2% lidocaine with:100,000 epinephrine for inferior alveolar nerve block. Anesth Prog 38:84-89, 1991.

24- Steffens JP, Pochapski MT, Santos FA, Pilatti GL. Efficacy of anesthetic agents to delay pain onset after periodontal surgery. Anesth prog 58:57-60, 2011.

25- Replogle K, Reader A, Nist R, Beck M, Weaver J, Meyers WJ.Anesthetic efficacy of the intraosseous injection of 2% lidocaine (1:100,000 epineph-rine) and 3% mepivacaine in mandibular first molars. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 83:30-37, 1997.

26- Hersh EV, Hermann DG, Lamp CL, Johnson PD, Mac- Afee K. Assessing the duration of mandibular soft tissue anesthesia. J AmDen-tAssoc.126:1531-1536, 1995.

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